Research and Development
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R&D EmployeesAt IOL, we keep pushing our boundaries in driving innovations through our constant research and development initiatives.We work on promising innovations, which can drive product and manufacturing science forward. As innovators work to find answers to critical medical questions, we focus our energy on partnering with them for delivering solutions for the current and future drug needs of pharmaceutical companies worldwide.
Our R&D efforts concentrate on developing products that intends to solve the needs of the pharmaceutical industry in terms of uninterrupted supply of superior quality products. While we do this, we also ensure that we develop eco-friendly processes that allow us to ensure sustainable supply of APIs to our customers.
Generic API Research
We mainly focus on the research of generics for therapeutic categories like Pain management, Drugs acting on Central Nervous Systems, Anti-allergic drugs, and lifestyle-related diseases such as Cardiovascular drugs, Anti Diabetics, and Anti-ulcer drugs.
IOL is amongst the leading API partners for pharmaceutical companies across the world. We have a prominent presence in domestic and international markets. We have a state-of-the-art R&D center situated in Punjab, India. We possess expertise in specialized chemistries such as Grignard reactions, Cyanation and Bromination reactions, High-temperature high-pressure reactions (Temperature up to 220oC and pressure up to 35 kg/cm2), Hydrogenation reactions (up to 20 kg/cm2), Chiral Resolution, Sodium metal reactions, Propylene, Chlorine and HCl gas-based reactions along with other varied chemical reactions.
When it comes to R&D, we always concentrate on 100% backward integration, the use of indigenously available raw materials, and in-house manufacturing of Key Starting Materials and intermediates with continuous improvement in processes from quality, cost, and effluent generation perspectives.
Our API R&D function is backed by a team of 50 qualified and dedicated researchers with highly specialized qualifications in Chemistry/Technology like PDF, Ph.D. in Chemistry and Pharmaceutical Technology, Master in Science, and Master in Pharmacy.
Our R&D division works round the clock and operates 24*6. It is well equipped with full-fledged process development laboratory with advanced analytical laboratory having latest analytical instruments such as LC-MS, Multi gradient High Performance Liquid Chromatography with PDA, RI and UV detectors, Gas Chromatography with Head space analysers, Malvern 3000 and 2000 particle size analyser, Infrared Spectroscopy, Ultraviolet spectroscopy and Digital Polarimetry. Our R&D function has tied up with local Universities and Testing laboratories for specialised and rare analytical requirements.
At IOL, our R&D is integrated by cGMP Pilot Plant (PP) for scale up trials. The PP is equipped with 0.5 KL to 1.0 KL SS and Glass lined Reactors, Powder Processing Area with HVAC system and Microniser with other supporting equipment and utility supply including oil heating system.
Intermediates Research
Our R&D division supports IOL’s Policy of 100% Atmanirbhayta for Key Starting Materials (KSMs) for all Active Pharmaceutical Ingredients (APIs) manufactured by IOL. All KSMs are developed and manufactured in-house such as Isobutylbenzene (IBB) for Ibuprofen, O-tolylbenzonitrile (OTBN) for Sartan series of products, and SABA HCl for Leviteracitam, amongst others, which is rare to see in other Indian API companies. Furthermore, this gives our customers the assurance of uninterrupted supply of the APIs.