We mainly focus on the research of generics for therapeutic categories like Pain management, Drugs acting on Central Nervous Systems, Anti allergic drugs and lifestyle related diseases such as Cardiovascular drugs, Anti Diabetics and Anti-ulcer drugs.
IOL is amongst the leading API partners for pharmaceutical companies across the world. We have a prominent presence in domestic and international markets. We have state-of-the-art R&D centre situated in Punjab, India. We possess expertise in specialised chemistries such as Grignard reactions, Cyanation and Bromination reactions, High temperature high pressure reactions (Temperature up to 220oC and pressure up to 35 kg/cm2), Hydrogenation reactions (up to 20 kg/cm2), Chiral Resolution, Sodium metal reactions, Propylene, Chlorine and HCl gas-based reactions along with other varied chemical reactions.
When it comes to R&D, we always concentrate on 100% backward integration, use of indigenously available raw materials, in-house manufacturing of Key Starting Materials and intermediates with continuous improvement in processes from quality, cost and effluent generation perspective.
Our API R&D function is backed by a team of 50 qualified and dedicated researchers with highly specialised qualification in Chemistry/Technology like PDF, Ph.D. in Chemistry and Pharmaceutical Technology, Master in Science, and Master in Pharmacy.
Our R&D division works round the clock and operates 24*6. It is well equipped with full-fledged process development laboratory with advanced analytical laboratory having latest analytical instruments such as LC-MS, Multi gradient High Performance Liquid Chromatography with PDA, RI and UV detectors, Gas Chromatography with Head space analysers, Malvern 3000 and 2000 particle size analyser, Infrared Spectroscopy, Ultraviolet spectroscopy and Digital Polarimetry. Our R&D function has tied up with local Universities and Testing laboratories for specialised and rare analytical requirements.
At IOL, our R&D is integrated by cGMP Pilot Plant (PP) for scale up trials. The PP is equipped with 0.5 KL to 1.0 KL SS and Glass lined Reactors, Powder Processing Area with HVAC system and Microniser with other supporting equipment and utility supply including oil heating system.
Our R&D division supports IOL’s Policy of 100% Atmanirbhayta for Key Starting Materials (KSMs) for all Active Pharmaceutical Ingredients (APIs) manufactured by IOL. All KSMs are developed and manufactured in-house such as Isobutylbenzene (IBB) for Ibuprofen, O-tolylbenzonitrile (OTBN) for Sartan series of products, and SABA HCl for Leviteracitam, amongst others, which is rare to see in other Indian API companies. Furthermore, this gives our customers the assurance of uninterrupted supply of the APIs.